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Series GSE120282 Query DataSets for GSE120282
Status Public on Apr 01, 2020
Title RNA-sequence data of liver sinusoidal endothelial cells from control and endothelial RBPj-deficent mice with liver fibrosis
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary Endothelial notch signaling dominantly regulates liver physiology and pathology. To further explore the role and mechanisms of endothelial notch in modulating development and progression of liver fibrogenesis, we established endothelial RBPj conditinal knock-out mice to specifically block notch activity in endothelium. After development of CCl4-induced liver fibrosis, SECs from control and RBPj knock-out mice were isolated and processed for RNA-seq.
Overall design mRNA profiles of SECs in control and endothelial RBPj knock-out mice with liver fibrosis were generated by RNA sequencing, in triplicate, using Illumina HiSeq 3000
Contributor(s) Wang L, Ruan B, Duan J
Citation(s) 34277612
Submission date Sep 21, 2018
Last update date Jul 20, 2021
Contact name Bai Ruan
Organization name Fourth Military Medical University
Street address No.169, Changle Road
City Xi'an
State/province Shannxi
ZIP/Postal code 710032
Country China
Platforms (1)
GPL21493 Illumina HiSeq 3000 (Mus musculus)
Samples (6)
GSM3397534 F-CT1
GSM3397535 F-CT2
GSM3397536 F-CT3
This SubSeries is part of SuperSeries:
GSE120283 RNA-sequence data of liver sinusoidal endothelial cells in quiescent versus fibrotic and wild-type versus endothelial RBPj-deficent mice
BioProject PRJNA492397
SRA SRP162308

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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE120282_ruanbai-2.xls.gz 4.1 Mb (ftp)(http) XLS
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Raw data are available in SRA
Processed data are available on Series record

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