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Series GSE121366 Query DataSets for GSE121366
Status Public on Sep 21, 2019
Title Gene expression profiling of Foxr2-induced brain tumors
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary The goal of this study is profile gene expression patterns of Foxr2-induced brain tumor cells. Foxr2 overexpression in the brain induced tumor formation in the olfactory bulb (OB) and the brainstem (BS) under the p53 deficient background. Tumor cells were cultured in vitro, which resulted in sphere formation. Sphere-forming cells were used for gene expression analysis. Immortalized primary astroglia (AG) was analzyed for comparison.
 
Overall design mRNA profiles of astroglia (AG), olfactory bulb (OB) tumor cells and brainstem (BS) tumor cells were generated by deep sequencing, in triplicate, using Illumina HiSeq3000.
 
Contributor(s) Koso H
Citation(s) 30976792
Submission date Oct 17, 2018
Last update date Sep 22, 2019
Contact name Hideto Koso
E-mail(s) kouso-tky@umin.ac.jp
Phone +81 3 5449 5664
Organization name Institute of Medical Science, The University of Tokyo
Lab Division of Molecular and Developmental Biology
Street address 4-6-1 Shirokanedai
City Minato-ku
State/province Tokyo
ZIP/Postal code 108-8639
Country Japan
 
Platforms (1)
GPL21493 Illumina HiSeq 3000 (Mus musculus)
Samples (9)
GSM3433333 AG_1
GSM3433334 AG_2
GSM3433335 AG_3
Relations
BioProject PRJNA497186
SRA SRP165954

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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE121366_normalized_counts.txt.gz 599.0 Kb (ftp)(http) TXT
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