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Series GSE12525 Query DataSets for GSE12525
Status Public on Apr 23, 2009
Title 5-methylcytosine ChIP-on-Chip (MeDIP) of sporadic amyotrophic lateral sclerosis and control human brains
Organism Homo sapiens
Experiment type Methylation profiling by genome tiling array
Summary This experiment series sought to detect genome-wide methylation in sporadic amyotrophic lateral sclerosis brains and compare it to normal control brains. Methylation across the whole genome was measured in brain DNA of 10 SALS patients and 10 neurologically-normal controls. Methylated DNA was immunoprecipitated and interrogated by Affymetrix GeneChip Human Tiling 2.0R Array Sets. Methylation calls were compared between SALS patients and controls at each methylated site.

Keywords: ChIP-Chip
Overall design 10 sporadic amyotrophic lateral sclerosis brain (lateral frontal cortex, Brodmann area 46) and 10 normal control brain (lateral frontal cortex, Brodmann area 46). 1 replicate sample repeated at different time (19a).
Contributor(s) Pamphlett R, Morahan JM
Citation(s) 19922134
Submission date Aug 22, 2008
Last update date Mar 21, 2017
Contact name Roger Pamphlett
Organization name University of Sydney
Street address Blackburn Bld
City University of Sydney
ZIP/Postal code 2006
Country Australia
Platforms (7)
GPL4910 [Hs35b_P01R] Affymetrix Human Tiling 2.0R Set, Array 1
GPL4911 [Hs35b_P02R] Affymetrix Human Tiling 2.0R Set, Array 2
GPL4912 [Hs35b_P03R] Affymetrix Human Tiling 2.0R Set, Array 3
Samples (148)
GSM314671 Brain-SALS01-ArrayA-rep1
GSM314672 Brain-CTRL02-ArrayA-rep1
GSM314673 Brain-SALS03-ArrayA-rep1
BioProject PRJNA112929

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE12525_RAW.tar 7.9 Gb (http)(custom) TAR (of BAR, CEL)
GSE12525_ReadMe_BAR_files.txt 942 b (ftp)(http) TXT
Processed data provided as supplementary file

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