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Series GSE125588 Query DataSets for GSE125588
Status Public on Jan 25, 2019
Title Single Cell RNA seq of Genetically Engineered Mouse Models of Pancreatic Adenocarcinoma
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary We report the scRNAseq profiles of three mouse models of pancreatic cancer: KIC, KPfC, KPC. Analyses demonstrate the existence of 2 molecular subtypes of cancer cells, 2 molecular subtypes of cancer associated fibroblasts, and 2 molecular subtypes of cancer associated macrophages.
Overall design Untreated mice were sacrificed at various time points prior to scRNA library generation: normal mouse at 60 days, early KIC mouse at 40 days, late KIC mouse at 60 days, late KPfC mouse at 60 days and KPC mouse at 6 months.
Contributor(s) Hosein AN, Brekken R
Citation(s) 31335328
Submission date Jan 24, 2019
Last update date Oct 15, 2019
Contact name Abdel Nasser Hosein
Organization name MD Anderson Cancer Center
Street address 6565 MD Anderson Blvd
City Houston
State/province Texas
ZIP/Postal code 77030
Country USA
Platforms (1)
GPL19057 Illumina NextSeq 500 (Mus musculus)
Samples (5)
GSM3577882 Normal Pancreas
GSM3577883 Early KIC
GSM3577884 Late KIC
BioProject PRJNA516878
SRA SRP181952

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Supplementary file Size Download File type/resource
GSE125588_RAW.tar 46.6 Mb (http)(custom) TAR (of MTX, TSV)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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