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| Status |
Public on Jul 31, 2022 |
| Title |
The effect of insulin treatment versus insulin resistance on microRNA expression in the hypothalamic neuronal cell line mHypoE-46. |
| Organism |
Mus musculus |
| Experiment type |
Non-coding RNA profiling by array
|
| Summary |
The goal of this study was to determine the microRNAs altered upon the development of insulin resistance in a murine hypothalamic Neuropeptide Y/Agouti-related Peptide expressing cell line mHypoE-46
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| Overall design |
Twelve samples were analyzed. This included two time points 4 and 24 hours post treatment with either vehicle (Phosphate Buffered Saline, PBS) or 100 nM of Insulin. The experiment was replicated three times independently.
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| Contributor(s) |
Belsham DD, Chalmers JA, Nazarians-Armavil A |
| Citation(s) |
34919671 |
| |
| Submission date |
Jan 31, 2019 |
| Last update date |
Oct 30, 2022 |
| Contact name |
Denise D Belsham |
| E-mail(s) |
d.belsham@utoronto.ca
|
| Phone |
4169467646
|
| Organization name |
University of Toronto
|
| Department |
Physiology
|
| Street address |
1 Kings College Circle MSB3346
|
| City |
Toronto |
| State/province |
ON |
| ZIP/Postal code |
M5S 1A8 |
| Country |
Canada |
| |
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| Platforms (1) |
| GPL26135 |
nCounter mouse miRNA code set (based on miRBase v15, 620 probes) |
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| Samples (12)
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| Relations |
| BioProject |
PRJNA518090 |
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