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Series GSE126113 Query DataSets for GSE126113
Status Public on Jan 21, 2021
Title ATAC-seq profiles of B cells and naive and activated T cells from human peripheral blood
Organism Homo sapiens
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Summary Mature B cells, CD4+ T cells and CD8+ T cells were isolated from the peripheral blood of two human donors. Naive CD4+ and CD8+ T cells were cultured for three days in the presence of Dynabeads Human T-Activator CD3/CD28 beads (Life Technologies, cat. no. 111.31D) to induce activation. The B cells and naive and activated T cells were profiled by ATAC-seq to determine chromatin accessibility.
Overall design Cells were isolated from two human donors, resulting in two biological replicates of each combination of cell type and activation status.
Contributor(s) Bediaga NG, Smyth GK
Citation(s) 33436846
Submission date Feb 05, 2019
Last update date Jan 21, 2021
Contact name Gordon K Smyth
Phone (+61 3) 9345 2326
Fax (+61 3) 9347 0852
Organization name Walter and Eliza Hall Institute of Medical Research
Department Bioinformatics
Lab Smyth
Street address 1G Royal Pde
City Parkville
State/province Vic
ZIP/Postal code 3052
Country Australia
Platforms (1)
GPL18573 Illumina NextSeq 500 (Homo sapiens)
Samples (10)
GSM3591799 Naive CD4+ T cells 1 ATAC-Seq
GSM3591800 Naive CD4+ T cells 2 ATAC-Seq
GSM3591801 Naive CD8+ T cells 1 ATAC-Seq
This SubSeries is part of SuperSeries:
GSE126117 RNA-seq, ATAC-seq and Hi-C profiles of B cells and naïve and activated T cells from human peripheral blood
BioProject PRJNA521045
SRA SRP183766

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE126113_PeakCounts.txt.gz 2.3 Mb (ftp)(http) TXT
GSE126113_PeakRegions.bed.gz 916.5 Kb (ftp)(http) BED
GSE126113_RAW.tar 10.9 Mb (http)(custom) TAR (of TXT)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file
Processed data are available on Series record

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