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Series GSE126278 Query DataSets for GSE126278
Status Public on Feb 13, 2019
Title Characterization of tumor-infiltrating T cells by TCR-β repertoire analyses
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary Local administration of IFN-α-producing proliferating myeloid cells (IFN-α-iPSC-pMCs) inhibited the tumor growth not only at the treatment site but also at the distant site (left). T cell receptor (TCR)-β chain repertoire and complementarity determining region 3 (CDR3) gene sequence analyses of tumor-infiltrating lymphocytes (TILs) showed marked enrichment of T cells with identical TCR-β chains in bilateral tumor tissues.
 
Overall design TCR-β repertoire analyses of IFN-α-iPSC-pMC-treated tumor, distant tumor, and spleen (2 mice)
 
Contributor(s) Uemura Y, Zhang R
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Submission date Feb 08, 2019
Last update date Feb 15, 2019
Contact name Ranmaru Shimoda
E-mail(s) shimoda@rhelixa.com
Phone +818043368250
Organization name Rhelixa, Inc.
Street address 3F Yayoi Bldg., 3-7-4 Iwamotocho
City Chiyoda
State/province Tokyo
ZIP/Postal code 101-0032
Country Japan
 
Platforms (1)
GPL16417 Illumina MiSeq (Mus musculus)
Samples (6)
GSM3595657 TCR_treated_tumor_01
GSM3595658 TCR_distant_tumor_01
GSM3595659 TCR_spleen_01
This SubSeries is part of SuperSeries:
GSE126281 Type I Interferon Delivery by iPSC-Derived Myeloid Cells Elicits Antitumor Immunity via XCR1+ Dendritic Cells
Relations
BioProject PRJNA521846
SRA SRP185725

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE126278_RAW.tar 1.0 Mb (http)(custom) TAR (of TXT)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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