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Series GSE128328 Query DataSets for GSE128328
Status Public on Dec 01, 2019
Title Gene expression profile in endometrial organoids cultured in normal follicular phase vs PCOS-like hormone profile
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary We generated scaffold-free endometrial organoids from human primary endometrial tissues. These organoids were subjected to stepwise hormone treatments for 14 days mimicking the proliferative phase of menstrual cycle or with constantly high testosterone mimicking PCOS conditions
 
Overall design Organoids from 4 patients were cultured in normal follicular phase and PCOS hormone profiles for 14 days and then subjected for RNAseq to determine genes differentially expressed in organoids cultured in PCOS condition.
 
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NIH grant(s)
Grant ID Grant title Affiliation Name
R01 CA243249 Understanding Progesterone Receptor action in Obesity for Endometrial Cancer Prevention NORTHWESTERN UNIVERSITY AT CHICAGO Ji-Yong Julie Kim
UH3 ES029073 PCOS and androgen-related disease modeling and drug testing in Multi-organ Integrated Microfluidic Reproductive Platform NORTHWESTERN UNIVERSITY AT CHICAGO Teresa K Woodruff
Submission date Mar 14, 2019
Last update date Dec 03, 2019
Contact name Julie Kim
E-mail(s) j-kim4@northwestern.edu
Phone 312-503-5377
Organization name Northwestern University
Department Obstetrics and Gynecology
Lab Lurie 4-250
Street address 303 E. Superior St
City Chicago
State/province IL
ZIP/Postal code 60611
Country USA
 
Platforms (1)
GPL20301 Illumina HiSeq 4000 (Homo sapiens)
Samples (8)
GSM3671466 CONTROL 1
GSM3671467 CONTROL 2
GSM3671468 CONTROL 3
Relations
BioProject PRJNA527131
SRA SRP188461

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE128328_RAW.tar 780.0 Kb (http)(custom) TAR (of TXT)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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