GEO Logo
   NCBI > GEO > Accession DisplayHelp Not logged in | LoginHelp
GEO help: Mouse over screen elements for information.
Series GSE128483 Query DataSets for GSE128483
Status Public on May 30, 2019
Title Dynamic chromatin structure during early ILC progenitor differentiation
Organism Mus musculus
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Summary To characterize the epigenomes during early ILC progenitor differentiation, we did DNase-seq, CUT&RUN and scMNase-seq assays in all-lymphoid progenitor (ALP), early innate lymphoid progenitor (EILP), and innate lymphoid cell progenitor (ILCP) cells.
Overall design We did the CUT&RUN for identifing genome-wide TCF1 binding in EILP cells and DNase-seq in ALP, EILP and ILCP cells. Samples that include "_tech1" or "_tech2" indicate that those samples with same GB identifier were technical repeats with different libraries made independently from the same RNA extraction.
Contributor(s) Ren G, Lai B, Zhao K
Citation(s) 31358996
Submission date Mar 18, 2019
Last update date Dec 22, 2019
Contact name Keji Zhao
Organization name NHLBI,NIH
Department Systems Biology Center
Lab Laboratory of Epigenome Biology
Street address 9000 Rockville Pike
City Bethesda
State/province MD
ZIP/Postal code 20892
Country USA
Platforms (1)
GPL21493 Illumina HiSeq 3000 (Mus musculus)
Samples (21)
GSM3677379 TCF1_CUT&RUN_EILP_rep1_GB3039
GSM3677380 TCF1_CUT&RUN_EILP_rep2_GB3048
GSM3677381 TCF1_CUT&RUN_EILP_rep3_GB6236_tech1
BioProject PRJNA527826
SRA SRP188745

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource 20.7 Mb (ftp)(http) WIG
GSE128483_ALP_WT_DHS_peaks.txt.gz 1.8 Mb (ftp)(http) TXT
GSE128483_EILP_IgG-W50-normalized.wig.gz 7.5 Mb (ftp)(http) WIG
GSE128483_EILP_TCF1-W50-normalized.wig.gz 6.2 Mb (ftp)(http) WIG
GSE128483_EILP_TCF1_peaks.txt.gz 127.6 Kb (ftp)(http) TXT 18.6 Mb (ftp)(http) WIG
GSE128483_EILP_WT_DHS_peaks.txt.gz 1.9 Mb (ftp)(http) TXT 21.0 Mb (ftp)(http) WIG
GSE128483_ILCP_WT_DHS_peaks.txt.gz 1.9 Mb (ftp)(http) TXT
SRA Run SelectorHelp
Raw data are available in SRA
Processed data are available on Series record

| NLM | NIH | GEO Help | Disclaimer | Accessibility |
NCBI Home NCBI Search NCBI SiteMap