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Series GSE128758 Query DataSets for GSE128758
Status Public on Aug 20, 2020
Title Neonatal hematopoietic stem and progenitor cell ontogeny at single cell resolution (ATAC-seq)
Organism Mus musculus
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Summary The goal of this study was to characterize the transcriptional changes that take place in hematopoietic stem and progenitor cells as they transit the neonatal period of development. These changes were observed at the single cell level and they are correlated with epigenome remodeling, as evidenced by the ATAC-seq and Chipmentation data (H3K4me1 and H3K27ac) in this data set.
 
Overall design (i) ATAC-seq analysis of HSCs and HPCs during fetal, neonatal and adult stages of development
(ii) ATAC-seq analysis of wild type and Ifnar-ko HSCs and HPCs at P7
The strain background for all experiments is B6
 
Contributor(s) Magee J
Citation(s) 32822583
Submission date Mar 24, 2019
Last update date Nov 23, 2020
Contact name Jeffery Magee
E-mail(s) magee_j@kids.wustl.edu
Organization name Washington University School of Medicine
Department Internal Medicine - Cardiovascular Division
Street address 660 S Euclid Ave.
City St Louis
State/province Missouri
ZIP/Postal code 63110
Country USA
 
Platforms (1)
GPL17021 Illumina HiSeq 2500 (Mus musculus)
Samples (35)
GSM3684451 fetal_HSC-1 ATAC-seq
GSM3684452 fetal_HSC-2 ATAC-seq
GSM3684453 fetal_HSC-3 ATAC-seq
This SubSeries is part of SuperSeries:
GSE128762 Neonatal hematopoietic stem and progenitor cell ontogeny at single cell resolution
Relations
BioProject PRJNA528803
SRA SRP189265

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE128758_BA_P7_48+LSK.fc.signal.bigwig 481.0 Mb (ftp)(http) BIGWIG
GSE128758_BA_P7_48+LSK.optimal_peak.narrowPeak.gz 2.2 Mb (ftp)(http) NARROWPEAK
GSE128758_BA_P7_HSC.fc.signal.bigwig 396.0 Mb (ftp)(http) BIGWIG
GSE128758_BA_P7_HSC.optimal_peak.narrowPeak.gz 1.6 Mb (ftp)(http) NARROWPEAK
GSE128758_Infnar_mm__P7_48+LSK.fc.signal.bigwig 491.4 Mb (ftp)(http) BIGWIG
GSE128758_Infnar_mm__P7_48+LSK.optimal_peak.narrowPeak.gz 2.1 Mb (ftp)(http) NARROWPEAK
GSE128758_Infnar_mm__P7_HSC.fc.signal.bigwig 197.1 Mb (ftp)(http) BIGWIG
GSE128758_Infnar_mm__P7_HSC.optimal_peak.narrowPeak.gz 1.4 Mb (ftp)(http) NARROWPEAK
GSE128758_P14_HPC.filt.narrowPeak.gz 2.8 Mb (ftp)(http) NARROWPEAK
GSE128758_P14_HPC.pooled.fc.signal.bigwig 676.8 Mb (ftp)(http) BIGWIG
GSE128758_P14_HSC.filt.narrowPeak.gz 2.7 Mb (ftp)(http) NARROWPEAK
GSE128758_P14_HSC.pooled.fc.signal.bigwig 348.9 Mb (ftp)(http) BIGWIG
GSE128758_P21_HPC.filt.narrowPeak.gz 2.3 Mb (ftp)(http) NARROWPEAK
GSE128758_P21_HPC.pooled.fc.signal.bigwig 429.8 Mb (ftp)(http) BIGWIG
GSE128758_P7_HPC.filt.narrowPeak.gz 2.2 Mb (ftp)(http) NARROWPEAK
GSE128758_P7_HPC.pooled.fc.signal.bigwig 336.4 Mb (ftp)(http) BIGWIG
GSE128758_adult_HPC.filt.narrowPeak.gz 2.6 Mb (ftp)(http) NARROWPEAK
GSE128758_adult_HPC.pooled.fc.signal.bigwig 768.6 Mb (ftp)(http) BIGWIG
GSE128758_adult_HSC.filt.narrowPeak.gz 3.1 Mb (ftp)(http) NARROWPEAK
GSE128758_adult_HSC.pooled.fc.signal.bigwig 1006.3 Mb (ftp)(http) BIGWIG
GSE128758_fetal_HPC.filt.narrowPeak.gz 2.7 Mb (ftp)(http) NARROWPEAK
GSE128758_fetal_HPC.pooled.fc.signal.bigwig 706.4 Mb (ftp)(http) BIGWIG
GSE128758_fetal_HSC.filt.narrowPeak.gz 3.1 Mb (ftp)(http) NARROWPEAK
GSE128758_fetal_HSC.pooled.fc.signal.bigwig 693.8 Mb (ftp)(http) BIGWIG
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Raw data are available in SRA
Processed data are available on Series record

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