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Status |
Public on May 30, 2019 |
Title |
Study to evaluate the effect of the type of tissue on gene expression measurements |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by array
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Summary |
To evaluate the effect of tissue type (cytology vs. surgical tissue) on gene expression measurements. Information was used to select probesets with a high spatial reproducibility for the development of gene signatures.
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Overall design |
88 breast cancer samples were obtained at the time of surgery prior to any systemic treatment. In addition to a solid tissue sample, a scrape (=cytology) sample was taken by scraping with a scalpel over the cut-surface of the tumor. Samples were stored in RNAlater and profiled on Affymetrix U133A microarrays.
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Contributor(s) |
Sinn BV, Symmans WF |
Citation(s) |
31231679 |
Submission date |
Apr 09, 2019 |
Last update date |
Jun 29, 2019 |
Contact name |
Bruno Valentin Sinn |
E-mail(s) |
bruno.sinn@charite.de
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Organization name |
University of Texas - MD Anderson Cancer Center
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Department |
Translational Molecular Pathology
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Lab |
W.F. Symmans
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Street address |
2130 W Holcombe Blvd
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City |
Houston |
State/province |
TX |
ZIP/Postal code |
77030 |
Country |
USA |
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Platforms (1) |
GPL96 |
[HG-U133A] Affymetrix Human Genome U133A Array |
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Samples (232)
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This SubSeries is part of SuperSeries: |
GSE124648 |
SET ER/PR - A robust 18-gene Predictor for Sensitivity to Endocrine Therapy for Metastatic Breast Cancer |
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Relations |
BioProject |
PRJNA531730 |