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Series GSE131227 Query DataSets for GSE131227
Status Public on Feb 23, 2020
Title HOS15 and HDA9 negatively regulate immunity through histone deacetylation on intracellular immune receptor NLR genes in Arabidopsis
Organism Arabidopsis thaliana
Experiment type Expression profiling by high throughput sequencing
Summary We isolated AtHOS15 as a negative regulator of plant immunity from genetic screen. To investigate how HOS15 influences plant immunity, we performed whole genome transcriptome (RNA-seq) analysis of the hos15-4 mutant. A total of 3,512 differentially expressed genes, with 1,870 upregulated and 1,642 downregulated, were found in hos15-4 mutant compared to wile-type Col-0. Gene Ontology analysis showed that genes involved in defense responses including immune receptor NLR genes are highly enriched among upregulated genes.
Overall design Examination of whole genome transriptome (RNA-seq) in hos15-4 mutant compared to wide-type Col-0. Two-week-old plants growing under constant light at 22C were used for RNA extraction.
Contributor(s) Hua J, Yang L
Citation(s) 31854111
Submission date May 15, 2019
Last update date Feb 23, 2020
Contact name Leiyun Yang
Organization name Cornell University
Department Plant Biology
Lab Jian Hua lab
Street address 360 Tower road
City Ithaca
State/province NY
ZIP/Postal code 14850
Country USA
Platforms (1)
GPL19580 Illumina NextSeq 500 (Arabidopsis thaliana)
Samples (6)
GSM3767879 WT Col-0 Rep 1
GSM3767880 WT Col-0 Rep 2
GSM3767881 WT Col-0 Rep 3
BioProject PRJNA543016
SRA SRP198449

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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE131227_hos15RNAseq_raw_reads_all.txt.gz 263.0 Kb (ftp)(http) TXT
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Processed data are available on Series record

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