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Status |
Public on Nov 30, 2008 |
Title |
(AKR/J x FVB/NJ)F1 versus (DBA/2J x FVB)F1 bone marrow expression data |
Organism |
Mus musculus |
Experiment type |
Expression profiling by array
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Summary |
F1 hybrids from (AKR/J x FVB/NJ) and (DBA/2J x FVB/NJ) outcrosses display a 20-fold difference in mammary tumor metastatic capacity, due to differences in inherited polymorphisms. Expression studies were performed to determine whether polymorphism-driven gene expression signatures predictive of outcome could be generated from normal tissues
Keywords: Basal transcription profiles
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Overall design |
Bone Marrow from adult F1 animals from (AKR/J x FVB/NJ) and (DBA/2J x FVB/NJ) outcrosses was collected and arrayed on Affymetrics chip to identify basal differences in gene expression between the different genotypes
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Contributor(s) |
Hunter KW |
Citation(s) |
19118016 |
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Submission date |
Oct 16, 2008 |
Last update date |
Feb 11, 2019 |
Contact name |
Kent Hunter |
E-mail(s) |
hunterk@mail.nih.gov
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Organization name |
National Cancer Institute
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Department |
Center for Cancer Research
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Lab |
Laboratory of Cancer Biology and Genetics
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Street address |
37/4048 37 Convent Drive
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City |
Bethesda |
State/province |
MD |
ZIP/Postal code |
20892-4264 |
Country |
USA |
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Platforms (1) |
GPL1261 |
[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array |
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Samples (6)
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This SubSeries is part of SuperSeries: |
GSE13231 |
The effect of inherited polymorphism on prognostic gene expression signatures |
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Relations |
BioProject |
PRJNA114043 |