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| Status |
Public on Jun 21, 2019 |
| Title |
Liver macrophages inhibit the endogenous antioxidant response in obesity-associated insulin resistance [RNA-Seq] |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Liver Macrophages exacerbate oxidative stress induced by hepatic steatosis in obesity by blocking the endogenous anti-oxidant response.
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| |
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| Overall design |
Kupffer cell mRNA profiles of wild type and obese mice at 9 and 14 weeks were generated by deep RNA sequencing, in replicates, using Illumina HiSeq 3000.
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| |
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| Contributor(s) |
Azzimato V, Jager J, Chen P, Aouadi M |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Jun 16, 2019 |
| Last update date |
Jun 21, 2019 |
| Contact name |
Ping Chen |
| E-mail(s) |
ping.chen@ki.se
|
| Organization name |
Karolinska Institutet
|
| Department |
Department of Laboratory Medicine
|
| Street address |
Alfred Nobels allé 8
|
| City |
Huddinge |
| ZIP/Postal code |
14157 Huddinge |
| Country |
Sweden |
| |
|
| Platforms (1) |
| GPL21493 |
Illumina HiSeq 3000 (Mus musculus) |
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| Samples (15)
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| This SubSeries is part of SuperSeries: |
| GSE132801 |
Liver macrophages inhibit the endogenous antioxidant response in obesity-associated insulin resistance |
|
| Relations |
| BioProject |
PRJNA549079 |
| SRA |
SRP201548 |
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