|
| Status |
Public on Oct 06, 2019 |
| Title |
Clonal selection confers distinct evolutionary trajectories in BRAF-driven cancers |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
Analysis of BRAF variant gene expression activity after constitutive variant expression in immortalized lung ephithelial cells. The hypothesis tested in the present study was that the level of BRAF activity will vary based on the identity of the variant expressed. Results provide important information on the variation and continous quality of BRAF activity across diverse variants that were tested.
|
| |
|
| Overall design |
Total mRNA obtained from BEAS2B cells transfected with BRAF variants
|
| |
|
| Contributor(s) |
Mohamed A, Abazeed ME |
| Citation(s) |
31723142 |
| |
| Submission date |
Jun 21, 2019 |
| Last update date |
Nov 25, 2019 |
| Contact name |
Mohamed E. Abazeed |
| Organization name |
Cleveland Clinic
|
| Department |
Radiation Oncology/Translational Hematology Oncology Research
|
| Street address |
2111 East 96th St/NE6-258
|
| City |
Clevleand |
| State/province |
OH |
| ZIP/Postal code |
44195 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL16791 |
Illumina HiSeq 2500 (Homo sapiens) |
|
| Samples (74)
|
|
| Relations |
| BioProject |
PRJNA550100 |
| SRA |
SRP202539 |
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