|
| Status |
Public on Apr 14, 2020 |
| Title |
Hi-C profiling of B-cell progenitors from Erg KO and WT mice |
| Organism |
Mus musculus |
| Experiment type |
Other
|
| Summary |
Hi-C was used to examine long range chromatin interactions in B cell progenitors in the presence and absence of the Erg transcription factor. Specifically, OP9 cultured B220+ B-cell progenitors derived from the bone marrow of Rag1CreT/+;ErgΔ/Δ mice and from Rag1CreT/+ and Rag1Cre+/+;Erg fl/fl control mice were isolated and DNA interactions were profiled by in situ Hi-C.
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| Overall design |
Hi-C profiling was performed for two biological replicates of progenitor B-cells from each of the three mouse genotypes: Rag1CreT/+;ErgΔ/Δ, Rag1CreT/+ and Rag1Cre+/+;Erg fl/fl.
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| |
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| Contributor(s) |
Coughlan HD, Smyth GK, Ng A |
| Citation(s) |
32541654 |
| |
| Submission date |
Jun 24, 2019 |
| Last update date |
Jun 22, 2020 |
| Contact name |
Gordon K Smyth |
| E-mail(s) |
smyth@wehi.edu.au
|
| Phone |
(+61 3) 9345 2326
|
| Fax |
(+61 3) 9347 0852
|
| URL |
http://www.wehi.edu.au
|
| Organization name |
Walter and Eliza Hall Institute of Medical Research
|
| Department |
Bioinformatics
|
| Lab |
Smyth
|
| Street address |
1G Royal Pde
|
| City |
Parkville |
| State/province |
Vic |
| ZIP/Postal code |
3052 |
| Country |
Australia |
| |
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| Platforms (1) |
| GPL19057 |
Illumina NextSeq 500 (Mus musculus) |
|
| Samples (6)
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| Relations |
| BioProject |
PRJNA550444 |
| SRA |
SRP211877 |
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