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Series GSE133342 Query DataSets for GSE133342
Status Public on Jun 27, 2019
Title Angptl8 mediates food-driven resetting of hepatic circadian clock in mice
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary Mammalian circadian clocks precisely control the rhythms of behavior and physiology, and can be reset by various environmental signals. While the light-dark (LD) cycle resets the master clock, timed food intake is a potent synchronizer of peripheral clocks. As the largest metabolic organ, the liver sensitively responds to the food signals and secrets hepatokines, leading to the robust regulation of metabolic and clock processes. However, it remains unknown which hepatokine mediates the food-driven resetting of the liver clock independent of the master clock. In our current study, we clustered high-throughput RNA sequencing results to screen out candidate genes that mediate the food-driven resetting of the liver clock
Overall design Total RNA after subjecting to fasting/re-feeding cycles or constant darkness were isolated from mice liver and seqenced using Illumina HiSeq 3000
Contributor(s) Chen S, Feng M, Zhang S, Dong Z, Wang Y, Zhang W
Citation(s) 31388006, 32160860
Submission date Jun 26, 2019
Last update date Mar 17, 2020
Contact name siyu chen
Organization name China Pharmaceutical University
Street address #639 longmian avenue
City nanjing
ZIP/Postal code 211198
Country China
Platforms (1)
GPL21493 Illumina HiSeq 3000 (Mus musculus)
Samples (9)
GSM3906007 ad-libitum
GSM3906008 fasted
GSM3906009 fasted-refed
BioProject PRJNA551214
SRA SRP212112

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE133342_RAW.tar 1.2 Mb (http)(custom) TAR (of TXT)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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