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Series GSE134509 Query DataSets for GSE134509
Status Public on Nov 21, 2019
Title Genome wide maps of chromatin states of larval Drosophila neural stem cells (NSCs), their progeny and their tumorigenic counterparts
Organism Drosophila melanogaster
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Summary We develop a FACS-based method to sort different cell types of larval Drosophila brain and perform chromatin immunoprecipitation with histone modifications: H3K4me3 for active mark and H3k27me3 for repressive mark. We then sequence chromatin immunoprecipitated DNA in order to examine the chromatin state changes in neurogenesis as well as in tumorigenesis.
Overall design examination of 2 histone modifications in four different cell types.
Contributor(s) Landskron L, Abdusselamoglu MD, Eroglu E, Bowman SK, Burkard TR, Kingston RE, Knoblich JA
Citation(s) 31748204
Submission date Jul 18, 2019
Last update date Dec 04, 2019
Contact name Merve Deniz Abdusselamoglu
Organization name Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA)
Street address Doktor. Bohr-Gasse 3
City Vienna
ZIP/Postal code 1030
Country Austria
Platforms (1)
GPL13304 Illumina HiSeq 2000 (Drosophila melanogaster)
Samples (30)
GSM3954654 type I neuroblasts replicate 1 (H3K4me3)
GSM3954655 type I neuroblasts replicate 2 (H3K4me3)
GSM3954656 brat RNAi neuroblasts replicate 1 (H3K4me3)
BioProject PRJNA555353
SRA SRP215291

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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE134509_RAW.tar 5.7 Mb (http)(custom) TAR (of TXT) 236.6 Mb (ftp)(http) BW 262.5 Mb (ftp)(http) BW 270.4 Mb (ftp)(http) BW 161.4 Mb (ftp)(http) BW 256.9 Mb (ftp)(http) BW 234.6 Mb (ftp)(http) BW 259.9 Mb (ftp)(http) BW 247.7 Mb (ftp)(http) BW 240.6 Mb (ftp)(http) BW 220.4 Mb (ftp)(http) BW 346.8 Mb (ftp)(http) BW 257.9 Mb (ftp)(http) BW 240.5 Mb (ftp)(http) BW 227.1 Mb (ftp)(http) BW 249.1 Mb (ftp)(http) BW 239.7 Mb (ftp)(http) BW
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Raw data are available in SRA
Processed data provided as supplementary file
Processed data are available on Series record

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