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| Status |
Public on Oct 16, 2019 |
| Title |
Gene expression profile of HMT3522 S1 cells grown on 2D and in 3D matrix in response to the death ligand TRAIL |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
The series represent gene expression profiles of HMT3522 S1 mammary epithelial cells cultured as 2D monolayers or in 3D reconstituted basement membrane (rBM) and treated with the death ligand TRAIL. Keywords: Genetic modification; response to death induction
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| Overall design |
Three replicated cultures were established for each of the 4 experiment groups, including S1 cells grown as 2D monolayers (S1-2D CA, S1-2D CB, S1-2D CC), S1 cells grown as 2D monolayers and treated with TRAIL (S1-2D TA, S1-2D TB, S1-2D TC), S1 cells embedded in 3D rBM (S1-3D CA, S1-3D CB, S1-3D CC), S1 cells embedded in 3D rBM and treated with TRAIL (S1-3D TA, S1-3D TB, S1-3D TC). Cells were embeded in rBM for 12 days and then treated with TRAIL (1 μg/mL) or vehicle for 8 hours before the collection of RNA samples.
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| Contributor(s) |
Tsai KK, Weaver VM |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Oct 15, 2019 |
| Last update date |
Oct 19, 2019 |
| Contact name |
Kelvin Kun-Chih Tsai |
| Organization name |
Taipei Medical University
|
| Department |
Graduate Institute of Clinical Medicine, College of Medicine
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| Lab |
Laboratory of Advanced Molecular Therapeutics
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| Street address |
7F, 250 Wuxing St, Xinyi Dist
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| City |
Taipei City |
| ZIP/Postal code |
11031 |
| Country |
Taiwan |
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| Platforms (1) |
| GPL96 |
[HG-U133A] Affymetrix Human Genome U133A Array |
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| Samples (12)
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| Relations |
| BioProject |
PRJNA577704 |
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