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Series GSE139106 Query DataSets for GSE139106
Status Public on Mar 22, 2020
Title Genomic profiles of tremolite-induced malignant peritoneal mesotheliomas developed in rats
Organism Rattus norvegicus
Experiment type Genome variation profiling by array
Summary Intraperitoneal injection of tremolite initiates mesothelial injury and chronic inflammation that causes the development of malignant mesothelioma (MM). We performed high-resolution comparative genomic hybridization to identify characteristics in the genomic profiles of tremolite-induced MMs in rats.
Overall design The carcinogenesis protocol was performed by intraperitoneal injection of 10 mg of tremolite in F1 hybrid (crossing Brown-Norway and Fischer344) rats. Genomes of 8 malignant peritoneal mesothelioma were profiled on Agilent 180K rat genome CGH microarrays.
Contributor(s) Yasumasa O, Shinya A, Shinya T
Citation(s) 32080953
Submission date Oct 18, 2019
Last update date Mar 25, 2020
Contact name Shinya Toyokuni
Organization name Nagoya University
Department Pathology
Street address 65 Tsuruma-Cho, Showa-Ku
City Nagoya
State/province Aichi
ZIP/Postal code 466-8550
Country Japan
Platforms (1)
GPL10451 Agilent-027064 SurePrint G3 Rat CGH Microarray 4x180K
Samples (8)
GSM4131042 Malignant mesothelioma 1
GSM4131043 Malignant mesothelioma 2
GSM4131044 Malignant mesothelioma 3
BioProject PRJNA578392

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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE139106_RAW.tar 403.8 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table

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