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| Status |
Public on Mar 22, 2020 |
| Title |
Genomic profiles of crocidolite-induced malignant peritoneal mesotheliomas developed in mice |
| Organism |
Mus musculus |
| Experiment type |
Genome variation profiling by genome tiling array
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| Summary |
Intraperitoneal injection of crocidolite initiates malignant peritoneal mesothelioma (MM) in mice. We performed high-resolution comparative genomic hybridization to identify characterstics in the genomic profiles of crocidolite-induced MM in the mice.
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| Overall design |
The carcinogenesis protocol was performed for five groups of wild type, Dmt1-transgenic, Mth1-knockout, Mutyh-knockout and Ogg1-knockout mice. Genomes of 20 malignant mesotheliomas were profiled on Agilent 180K mouse genome CGH microarrays.
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| Contributor(s) |
Okazaki Y, Funahashi S, Akatsuka S, Toyokuni S |
| Citation(s) |
32183600 |
| |
| Submission date |
Oct 21, 2019 |
| Last update date |
Mar 25, 2020 |
| Contact name |
Shinya Toyokuni |
| E-mail(s) |
akatsuka@med.nagoya-u.ac.jp
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| Organization name |
Nagoya University
|
| Department |
Pathology
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| Street address |
65 Tsuruma-Cho, Showa-Ku
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| City |
Nagoya |
| State/province |
Aichi |
| ZIP/Postal code |
466-8550 |
| Country |
Japan |
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| Platforms (1) |
| GPL10449 |
Agilent-027411 SurePrint G3 Mouse CGH Microarray 4x180K (Feature Number version) |
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| Samples (20)
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| Relations |
| BioProject |
PRJNA578701 |
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