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Series GSE140406 Query DataSets for GSE140406
Status Public on Dec 07, 2020
Title WWOX gene and estrogen receptor interplay in breast cancer
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary The aim of presented study was to assess the relationship between the presence of estrogen receptor and WWOX gene in breast cancer cell lines.
Overall design The study was based on estrogen-responsive (MCF7) and estrogen-unresponsive (MDA-MB-231, BT20) cell lines, for which depending on native expression, WWOX gene was either induced by retroviral transfection (MDA-MB-231) or silenced with shRNA (MCF7, BT20), and changes in the phenotype were estrogen stimulated. We have employed nAnT-iCAGE methodology for high-throughput gene expression profiling.
Contributor(s) Bednarek AK, Pospiech K
Citation(s) 35290621
Submission date Nov 14, 2019
Last update date Apr 27, 2022
Contact name Andrzej K. Bednarek
Phone +48 604583839
Organization name Medical University in Lodz
Department Department of Molecular Carcinogenesis
Street address Zeligowskiego St. 7/9
City Lodz
ZIP/Postal code 90-752
Country Poland
Platforms (1)
GPL21697 NextSeq 550 (Homo sapiens)
Samples (30)
GSM4160691 MDA-MB-231_vector_0
GSM4160692 MDA-MB-231_vector_3E2
GSM4160693 MDA-MB-231_vector_3VC
BioProject PRJNA589614
SRA SRP229975

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SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE140406_BT20_TSScoordinates_TPMexpression_all_samples_F5mapped.txt.gz 987.6 Kb (ftp)(http) TXT
GSE140406_MCF7_TSScoordinates_TPMexpression_all_samples_F5mapped.txt.gz 975.6 Kb (ftp)(http) TXT
GSE140406_MDA_TSScoordinates_TPMexpression_all_samples_F5mapped.txt.gz 1.2 Mb (ftp)(http) TXT
GSE140406_RAW.tar 15.5 Mb (http)(custom) TAR (of TXT)
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Raw data are available in SRA
Processed data provided as supplementary file
Processed data are available on Series record

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