GEO Logo
   NCBI > GEO > Accession DisplayHelp Not logged in | LoginHelp
GEO help: Mouse over screen elements for information.
Series GSE143304 Query DataSets for GSE143304
Status Public on Feb 24, 2020
Title Genome wide anaylsis of transcriptome modifications in male mice exposed to tributyltin during development
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary Purpose: To identify alterations induced by developmental exposure to tributyltin at different stages of life
Methods: Dams were treated with tributyltin during gestation and lactation in drinking water and pups were euthanized at different ages
Results: We identified a number of changes in transcriptomic activity in 5 month, and ten month old pups after tributyltin exposure. Male animals exposed to tributyltin also developed fatty liver 5 months of age and adenomas of the liver at ten months of age.
Overall design Liver was isolated from animals exposed to tributyltin during development at 5 months and 10 months. At 10 months of age adenomas were also collected.
Contributor(s) Walker C, Coarfa C
Citation(s) 31939706
Submission date Jan 08, 2020
Last update date Feb 24, 2020
Contact name Cheryl L Walker
Organization name Baylor College of Medicine
Department Center for Precision Environmental Health
Street address 1 Baylor Plaza
City Houston
State/province TX
ZIP/Postal code 77030
Country USA
Platforms (1)
GPL21493 Illumina HiSeq 3000 (Mus musculus)
Samples (29)
GSM4256746 TBT 10 month 10 10M10T
GSM4256747 TBT 10 month 11 11M10T
GSM4256748 TBT 10 month 12 12M10T
BioProject PRJNA599950
SRA SRP240390

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE143304_U01-Liver-Blood-June2019.featureCounts.coding_genes.EHP-GEO.xlsx 3.5 Mb (ftp)(http) XLSX
SRA Run SelectorHelp
Raw data are available in SRA
Processed data are available on Series record

| NLM | NIH | GEO Help | Disclaimer | Accessibility |
NCBI Home NCBI Search NCBI SiteMap