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Series GSE143500 Query DataSets for GSE143500
Status Public on Feb 18, 2020
Title A novel population of pro-inflammatory T cells that co-express αβ and γδ T cell receptors
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary To understand these pro-inflammatory effects of hybrid αβ-γδ T cells in detail, we carried out a transcriptomic analysis of hybrid αβ-γδ T cells and conventional γδ T cells isolated from the LNs of WT mice at rest and during EAE.
Overall design 20 samples analysed, 5 mice per group no pooling of samples. Control samples were Vy4 T cells from 5 naïve mice and hybrid Vy4 T cells from 5 naïve mice. Experimental samples were Vy4 T cells from 5 mice with EAE and hybrid Vy4 T cells from 5 mice with EAE
Contributor(s) Mills K, Edwards S, Roche F, Sutton C, Hokamp K, Pivorunas V, Dowding L, Macoritto M, Paez-Cortez J, Slavin A
Citation(s) 32106283
Submission date Jan 13, 2020
Last update date May 19, 2020
Contact name Karsten Hokamp
Phone +35318962719
Organization name Trinity College Dublin
Department Smurfit Institute of Genetics
Street address College Green
City Dublin
ZIP/Postal code 2
Country Ireland
Platforms (1)
GPL21493 Illumina HiSeq 3000 (Mus musculus)
Samples (20)
GSM4260812 vy4_cells_control1
GSM4260813 vy4_cells_control2
GSM4260814 vy4_cells_control3
BioProject PRJNA600830
SRA SRP241684

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Supplementary file Size Download File type/resource
GSE143500_Normalised_gene_based_counts_summary_naive_conv_vs_naive_hybrid.txt.gz 1.5 Mb (ftp)(http) TXT
GSE143500_Normalised_gene_based_counts_summary_naive_vs_EAE.txt.gz 2.8 Mb (ftp)(http) TXT
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