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Series GSE146628 Query DataSets for GSE146628
Status Public on Jan 25, 2021
Title Identification of Natural Antisense Transcripts in Mouse Brain and Their Association with Autism Spectrum Disorder Risk Genes
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary We performed strand-specific, deep RNA sequencing to profile expression of sense and antisense reads with a focus on 100 ASD-related genes in medial prefrontal cortex (mPFC) and striatum across mouse development (P7, P14 and P56). Using de novo transcriptome assembly, we generated a comprehensive long non-coding RNA (lncRNA) transcriptome. We conducted BLAST analyses to compare the resultant transcripts with the human genome and identified transcripts with high sequence similarity and coverage.
Overall design Strand specific deep RNA sequencing of medial prefrontal cortex (mPFC) and striatum across mouse development.
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Contributor(s) Koç B, Hall BJ, Fucile G, Giroud N, Bergauer T, Schmucki R
Citation(s) 33716665
Submission date Mar 09, 2020
Last update date Mar 16, 2021
Contact name Roland Schmucki
Organization name F. Hoffmann - La Roche AG
Street address Grenzacherstrase
City Basel
ZIP/Postal code 4058
Country Switzerland
Platforms (1)
GPL17021 Illumina HiSeq 2500 (Mus musculus)
Samples (24)
GSM4399903 P7_1_mPFC
GSM4399904 P7_2_mPFC
GSM4399905 P14_1_mPFC
BioProject PRJNA611551
SRA SRP252058

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SOFT formatted family file(s) SOFTHelp
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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE146628_GRCm38_no_lncRNA_wFilteredContigs.gtf.gz 25.4 Mb (ftp)(http) GTF
GSE146628_GRCm38_wFilteredAScontigs_ENScounts_final.mtx.gz 1.2 Mb (ftp)(http) MTX
GSE146628_GRCm38_wFilteredAScontigs_TRINcounts_final.mtx.gz 1.6 Mb (ftp)(http) MTX
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Raw data are available in SRA
Processed data are available on Series record

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