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Status |
Public on Dec 01, 2020 |
Title |
Multi-parametric profiling of a large panel of engineered nanomaterials (ENM) points to surface chemistry as a key determinant of nanomaterial effects |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by array
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Summary |
Monocytic, cancer derived THP-1 cells were exposed to 31 different engineered nanomaterials (ENMs) with different core chemistries and surface modifications for 24 hours.
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Overall design |
96 RNA samples treated with different ENM were analyzed against control samples. Cell culture medium without EMNs was used as negative control. Each condition was performed in triplicate. These are dual channel microarrays processed as single-channel arrays.
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Contributor(s) |
Gallud A, Delaval M, Kinaret P, Fortino V, Marwah V, Ytterberg J, Zubarev R, Skoog T, Kere J, Correia M, Loeschner K, Al-Ahmady Z, Ruiz J, Astruc D, Monopoli M, Handy R, Moya S, Savolainen K, Alenius H, Greco D, Fadeel B |
Citation(s) |
33240770 |
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Submission date |
Apr 15, 2020 |
Last update date |
Dec 01, 2020 |
Contact name |
Dario Greco |
E-mail(s) |
dario.greco@tuni.fi
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Organization name |
Tampere University
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Department |
Faculty of Medicine and Health Technology
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Lab |
Finnish Hub for Development and Validation of Integrated Approaches (FHAIVE)
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Street address |
Arvo ylpön Katu 34
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City |
Tampere |
ZIP/Postal code |
33520 |
Country |
Finland |
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Platforms (1) |
GPL20844 |
Agilent-072363 SurePrint G3 Human GE v3 8x60K Microarray 039494 [Feature Number Version] |
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Samples (96)
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Relations |
BioProject |
PRJNA625670 |
Supplementary file |
Size |
Download |
File type/resource |
GSE148705_RAW.tar |
571.9 Mb |
(http)(custom) |
TAR (of TXT) |
Processed data included within Sample table |
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