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Series GSE149521 Query DataSets for GSE149521
Status Public on Jul 27, 2020
Title Genome-wide DNA methylation analysis of lung carcinoma II
Organism Homo sapiens
Experiment type Methylation profiling by genome tiling array
Summary Complements GSE56044 with 36 additional samples belonging to the large-cell carcinoma (LCC) and large-cell neuroendocrine (LCNEC) histologies. LCC classification is according to WHO 2004 guidelines.
Genomic DNA from 36 lung cancer samples was treated with bisulfite and hybridized to Illumina methylation 450K arrays using standard protocols. Signal intensities were obtained from GenomeStudio (Illumina), converted to beta-values, filtered, and normalized to remove biases between Infinium I and II probes. Both raw intensity values, signal detection p-values and the final normalized data are included for each sample.
 
Overall design Genome-wide DNA methylation analysis of 36 lung carcinomas using Illumina Human Methylation 450K v1.0 Beadchips.
 
Contributor(s) Staaf J, Aine M
Citation(s) 32707835
Submission date Apr 28, 2020
Last update date Jul 29, 2020
Contact name Johan Staaf
Organization name SCIBLU - Swegene Centre for Integrative Biology at Lund University
Street address Medicon Village
City Lund
ZIP/Postal code SE-223 81
Country Sweden
 
Platforms (1)
GPL13534 Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482)
Samples (36)
GSM4504336 Lung cancer LU10
GSM4504337 Lung cancer LU370
GSM4504338 Lung cancer LU101
Relations
BioProject PRJNA628977

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE149521_GPL13534_200423_LNEC36_matrix_signal_intensities.txt.gz 90.0 Mb (ftp)(http) TXT
GSE149521_RAW.tar 183.1 Mb (http)(custom) TAR
Processed data included within Sample table

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