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Series GSE14982 Query DataSets for GSE14982
Status Public on Feb 27, 2009
Title Reprogramming human fat cells into iPS cells
Organism Homo sapiens
Experiment type Expression profiling by array
Summary This study determined whether human adipose stem cells (hASCs) could be reprogrammed into induced pluripotent stem (iPS) cells using the 4 factors OCT4, SOX2, KLF4, and cMYC. We showed successfull reprogramming could be achieved in which fat/adipose cells were able to assume embryonic-like phenotypes after lentiviral transduction with the 4 factors. Further, we believe these fat cells are intrinsically better-suited for reprogramming compared to fibroblasts, and result in higher yields of iPS cells.
Overall design Microarray study was performed in duplicates (hASCs, iPS cells derived from hASCs, and hESCs). Reference control was pooled RNA taken from H9 hESCs, embryoid bodies, and some differentiated cell types such as endothelial cells.
Citation(s) 19805220
Submission date Feb 24, 2009
Last update date Feb 22, 2018
Contact name Kitchener D. Wilson
Organization name Stanford University
Street address S140 Grant Bldg
City Stanford
State/province CA
ZIP/Postal code 94305
Country USA
Platforms (1)
GPL4133 Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Feature Number version)
Samples (6)
GSM348001 hESC-1
GSM348002 hESC-2
GSM374067 hASC-1
BioProject PRJNA111889

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE14982_RAW.tar 59.7 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table

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