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Series GSE150891 Query DataSets for GSE150891
Status Public on Sep 09, 2020
Title Expression data in EC109 and KYSE510 cells
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Esophageal cancer is the top 10 global arising common cancer with limited therapeutic strategies, and the general prognosis is poor owing to diagnosis in late stages in many cases. Sulforaphene (SFE) has been possess anticarcinogenic activities in many cancers, however, it is still not clear how SFE can function as an antineoplastic compound in esophageal cancer.
We used microarrays to identify the target genes involved in SFE inhibition of esophageal cancer cell progression.
 
Overall design EC109 and KYSE510 cells were cultured and treated with 20 µM SFE or DMSO as negative control for RNA extraction and hybridization on Affymetrix microarrays. We sought to obtain the significantly differentially expressed genes between SFE-treated cells and the control group.
 
Contributor(s) Han S, Wang Z
Citation(s) 32873775
Submission date May 19, 2020
Last update date Sep 09, 2020
Contact name sichong han
E-mail(s) hansichong@cicams.ac.cn
Organization name beijing university of chemical technology
Street address No. 15 North Third Ring East Road, Chaoyang District
City beijing
ZIP/Postal code 100029
Country China
 
Platforms (1)
GPL17586 [HTA-2_0] Affymetrix Human Transcriptome Array 2.0 [transcript (gene) version]
Samples (4)
GSM4560319 EC109_DMSO-treated cells
GSM4560320 EC109_20 µM SFE-treated cells
GSM4560321 KYSE510_DMSO-treated cells
Relations
BioProject PRJNA633944

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE150891_RAW.tar 89.2 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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