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| Status |
Public on Jun 05, 2020 |
| Title |
Multi-omics analysis reveals divergent epigenetic regulation of gene expression and drivers of esophageal squamous cell carcinoma [ChIP-seq] |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
Purpose: Epigenetic landscapes can shape physiologic and disease phenotypes. We used whole genome bisulfite sequencing, RNAseq, and ChIP-seq technologies to understand the methylome profiling, gene expression and regulation via epigenetic alterations on esophageal sequamouse carcinoma comparing to adjacent non-tumor tissues.
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| |
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| Overall design |
Methods: Cultured cells were used to examine EZH2 binding regions across genome.
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| |
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| Contributor(s) |
Wu W, Cao W |
| Citation(s) |
32699215 |
| |
| Submission date |
Jun 04, 2020 |
| Last update date |
Jul 27, 2020 |
| Contact name |
Wei Wu |
| E-mail(s) |
wei.wu@ucsf.edu
|
| Phone |
4157669898
|
| Organization name |
University of California, San Franciso
|
| Department |
Department of Medicine
|
| Lab |
Trever Bivona
|
| Street address |
600 16th street
|
| City |
San Francisco |
| State/province |
CA |
| ZIP/Postal code |
94143 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL20301 |
Illumina HiSeq 4000 (Homo sapiens) |
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| Samples (2) |
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| This SubSeries is part of SuperSeries: |
| GSE149612 |
Multi-omics analysis reveals divergent epigenetic regulation of gene expression and drivers of esophageal squamous cell carcinoma |
|
| Relations |
| BioProject |
PRJNA637386 |
| SRA |
SRP266023 |
