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Series GSE152577 Query DataSets for GSE152577
Status Public on Jun 06, 2023
Title The transcription factor Bcl6 represses active Notch signalling in fetal thymocytes
Organism Mus musculus
Experiment type Expression profiling by array
Summary We used Affymetrix microarrays to understand the genome wide differences between DMSO and Bcl6 inhibitor (79-6) anti-CD3 treated Rag1-/- E17.5 thymocytes (n=2) .
Overall design Thy1.2+ cells were sorted from anti-CD3 stimulated Rag1-/- FTOCs after 40 hours with treatment with 50uM 79-6 or DMSO alone, compared to fresh E17.5 thymi unstimulated time zero controls (n=2). RNA extracted from these sorted cells was used to perform microarrays.
Contributor(s) Solanki A, Sahni H, Crompton T
Citation(s) 32907850
Submission date Jun 16, 2020
Last update date Jun 07, 2023
Contact name Tessa Crompton
Organization name UCL
Department Immunobiology
Street address 30 Guilford Street
City London
ZIP/Postal code WC1N 1EH
Country United Kingdom
Platforms (1)
GPL6246 [MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [transcript (gene) version]
Samples (6)
GSM4618394 Control-0h-Rep1
GSM4618395 Control-0h-Rep2
GSM4618396 Control-DMSO-40h-Rep1
BioProject PRJNA639775

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE152577_RAW.tar 26.0 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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