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Series GSE152587 Query DataSets for GSE152587
Status Public on Aug 24, 2020
Title single-cell RNA-sequencing of murine intestine 24 hours following acute p53 activation due to Mdm2-loss (Mdm2FM/- Cag-CreERTg (FMTg)) compared to intestine that retain Mdm2 (Mdm2+/- Cag-CreERTg (Tg))
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary FMTg (Mdm2FM/- Cag-CreERTg) and Tg (Mdm2+/- Cag-CreERTg) mice were administered 6mg/40g of Tamoxifen dissolved in corn-oil and sacrificed 24 hours after injection. Single cells were isolated from fresh small intestine samples to compare single cell transcriptomes between intestine with high or control p53 activity
Overall design One FMTg small intestine and one Tg small intestine were isolated from mice 24 hours following a single 6mg/40g tamoxifen injection. Single cells were isolated from fresh tissues and then processed through the 10X genomics platform
Contributor(s) Moyer SM, Qi Y
Citation(s) 32900967
Submission date Jun 16, 2020
Last update date Dec 01, 2020
Contact name Yuan Qi
Organization name University of Texas M.D. Anderson Cancer Center
Department Bioinformatics & Computational Biology
Street address 1400 Pressler St
City Houston
State/province TX
ZIP/Postal code 77030-4008
Country USA
Platforms (1)
GPL24247 Illumina NovaSeq 6000 (Mus musculus)
Samples (2)
GSM4618457 Tg_Intestine
GSM4618458 FMTg_Intestine
BioProject PRJNA639792
SRA SRP267521

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SOFT formatted family file(s) SOFTHelp
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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE152587_RAW.tar 27.1 Mb (http)(custom) TAR (of TSV)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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