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| Status |
Public on Mar 15, 2010 |
| Title |
Effects of far-infrared rays on 3 human prostate cancer cell lines |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
We introduce anticancer effect of the far-infrared rays. The growth of three human prostate cancer cells (DU145, PC-3 and LNCaP) was suppressed in vitro only by far-infrared rays. The far-infrared rays induced the gene activation involved in apoptosis that exert positive effects on cancer control. Shima, H. et al. Far-infrared rays control prostate cancer cells in vitro and in vivo. Nature Precedings, hdl:10101/npre.12008.11980.10101 (2008).
Keywords: cancer control
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| Overall design |
Twelve samples were analyzed. Each sample was cultured quadricate. One replicate per array. The DU145, PC-3 and LNCaP cell lines were obtained from American Type Culture Collection (Manassas, VA, USA). DU145 cells were maintained in minimum essential medium supplemented with 10% heat-inactivated fetal calf serum, 2 mM L-glutamine, 100 U/ml penicillin G and 0.1 mM non-essential amino acids in an atmosphere of 5% CO2 at 37°C. PC-3 and LNCaP cells were maintained in F-12K medium and RPMI medium with the same supplements, respectively. All three cancer cells were cultured for 21 and 28 days with or without exposure to far-infrared rays. The cells without exposure to far-infrared rays were used as the reference samples (Far-infrared rays-treated vs. non-treated cells). Natural or synthetic rubber/resin (RB) was obtained as far-infrared rays emitter from Yamamoto Corporation (Osaka, Japan). RB consisted of rubber, lime stone and titanium metal powder in a honeycomb structure comprised of micron-sized cells, and had the ability to radiate far-infrared rays (4–25 um). Experimental samples were sandwiched with RBs for 21 and 28 days. Channels 1 were exposed to RB.
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| Contributor(s) |
Shima H, Qiu J, Yoshikawa Y |
| Citation |
Far-infrared rays control prostate cancer cells in vitro and in vivo. Cent. Eur. J. Biol. 5(2) 2010 178-189. doi: 10.2478/s11535-010-0003-7.
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| Submission date |
Mar 17, 2009 |
| Last update date |
Mar 21, 2012 |
| Contact name |
Hiroki Shima |
| E-mail(s) |
shima@siqm.org
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| Phone |
81-6-6372-8755
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| Organization name |
SHIMA Institution for Quantum Medicine
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| Street address |
3-7-41 Nakatsu YAMAMOTO Bild. 4F. Kitaku
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| City |
Osaka |
| ZIP/Postal code |
531-0071 |
| Country |
Japan |
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| Platforms (1) |
| GPL8312 |
IntelliGene® HS Human Expression CHIP (Array A&B) |
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| Samples (6)
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| This SubSeries is part of SuperSeries: |
| GSE15266 |
Effects of far-infrared rays on prostate cancer cells and normal prostate epithelial cells |
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| Relations |
| BioProject |
PRJNA123141 |
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