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| Status |
Public on Feb 23, 2021 |
| Title |
Epigenetic profiling to identify a human effector regulatory T cell core signature [H3K27ac] |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
We investigated the active enhancer landscape of human Treg in an autoimmune-associated inflammatory environment, i.e. synovial fluid (SF) from inflamed joints of Juvenile Idiopathic Arthritis (JIA) to improve our understanding of human effector Treg programming.
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| |
|
| Overall design |
Examination of H3K27acmodifications in 3 biological replicates of each healthy adult peripheral blood and Juvenile Idiopathic Arthritis patient synovial fluid regulatory T cells.
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| |
|
| Contributor(s) |
Lutter L, van Wijk F, van Loosdregt J, Mokry M |
| Citation(s) |
33976194 |
| |
| Submission date |
Aug 18, 2020 |
| Last update date |
Jun 21, 2021 |
| Contact name |
Lisanne Lutter |
| E-mail(s) |
L.Lutter-2@umcutrecht.nl
|
| Organization name |
University Medical Center Utrecht
|
| Street address |
Lundlaan 6
|
| City |
Utrecht |
| ZIP/Postal code |
3584 EA |
| Country |
Netherlands |
| |
|
| Platforms (1) |
| GPL18573 |
Illumina NextSeq 500 (Homo sapiens) |
|
| Samples (6)
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| This SubSeries is part of SuperSeries: |
| GSE156418 |
Epigenetic profiling to identify a human effector regulatory T cell core signature |
|
| Relations |
| BioProject |
PRJNA657861 |
| SRA |
SRP277940 |
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