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Series GSE157452 Query DataSets for GSE157452
Status Public on Sep 23, 2021
Title HNF4A defines tissue-specific circadian rhythms by beaconing BMAL1::CLOCK chromatin binding and shaping rhythmic chromatin landscape
Organisms Homo sapiens; Mus musculus
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Summary ChIP-seqs of BMAL1, HNF4A, FOXA2, H3K4me1, and H3K27ac were profiled in mouse liver tissues upon Hnf4a or Bmal1 knockout. BMAL1, H3K4me1, and H3K27ac ChIP-seq were profiled in U2OS cells ectopically expressing HNF4A.
 
Overall design Examination of BMAL1 genome binding and histone modifications distribution in Hnf4a knockout or HNF4A ectopic expression systems.
 
Contributor(s) Qu M, Qu H, Jia Z, Kay SA
Citation(s) 34732735
Submission date Sep 03, 2020
Last update date Nov 05, 2021
Contact name Meng Qu
E-mail(s) marciaqu@gmail.com
Phone 626-898-2391
Organization name University of Southern California
Department Keck Medical School
Lab Steve Kay lab
Street address 1002 West Childs Way
City Los Angeles
State/province California
ZIP/Postal code 90089
Country USA
 
Platforms (2)
GPL20301 Illumina HiSeq 4000 (Homo sapiens)
GPL21103 Illumina HiSeq 4000 (Mus musculus)
Samples (83)
GSM5288521 HWT_BMAL1_ChIPseq_1
GSM5288522 HWT_BMAL1_ChIPseq_2
GSM5288523 HWT_BMAL1_ChIPseq_3
Relations
BioProject PRJNA661328
SRA SRP280024

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE157452_BKO_FOXA2_ZT16_ChIP_merged.bw 374.1 Mb (ftp)(http) BW
GSE157452_BKO_FOXA2_ZT16_ChIP_merged.narrowPeak.gz 306.1 Kb (ftp)(http) NARROWPEAK
GSE157452_BKO_H3K27ac_ZT16_ChIP_merged.bw 480.7 Mb (ftp)(http) BW
GSE157452_BKO_H3K27ac_ZT16_ChIP_merged.narrowPeak.gz 682.2 Kb (ftp)(http) NARROWPEAK
GSE157452_BKO_H3K4me1_ZT16_ChIP_merged.bw 323.6 Mb (ftp)(http) BW
GSE157452_BKO_H3K4me1_ZT16_ChIP_merged.narrowPeak.gz 1.6 Mb (ftp)(http) NARROWPEAK
GSE157452_BKO_HNF4A_ZT16_ChIP_merged.bw 430.6 Mb (ftp)(http) BW
GSE157452_BKO_HNF4A_ZT16_ChIP_merged.narrowPeak.gz 356.2 Kb (ftp)(http) NARROWPEAK
GSE157452_BWT_FOXA2_ZT16_ChIP_merged.bw 360.2 Mb (ftp)(http) BW
GSE157452_BWT_FOXA2_ZT16_ChIP_merged.narrowPeak.gz 283.1 Kb (ftp)(http) NARROWPEAK
GSE157452_BWT_H3K27ac_ZT16_ChIP_merged.bw 487.4 Mb (ftp)(http) BW
GSE157452_BWT_H3K27ac_ZT16_ChIP_merged.narrowPeak.gz 702.1 Kb (ftp)(http) NARROWPEAK
GSE157452_BWT_H3K4me1_ZT16_ChIP_merged.bw 302.5 Mb (ftp)(http) BW
GSE157452_BWT_H3K4me1_ZT16_ChIP_merged.narrowPeak.gz 1.5 Mb (ftp)(http) NARROWPEAK
GSE157452_BWT_HNF4A_ZT16_ChIP_merged.bw 420.4 Mb (ftp)(http) BW
GSE157452_BWT_HNF4A_ZT16_ChIP_merged.narrowPeak.gz 569.9 Kb (ftp)(http) NARROWPEAK
GSE157452_HKO_BMAL1_ZT6_ChIP_merged.bw 400.8 Mb (ftp)(http) BW
GSE157452_HKO_BMAL1_ZT6_ChIP_merged.narrowPeak.gz 35.1 Kb (ftp)(http) NARROWPEAK
GSE157452_HKO_H3K27ac_ZT6_ChIP_merged.bw 478.7 Mb (ftp)(http) BW
GSE157452_HKO_H3K27ac_ZT6_ChIP_merged.narrowPeak.gz 161.3 Kb (ftp)(http) NARROWPEAK
GSE157452_HKO_H3K4me1_ZT6_ChIP_merged.bw 332.4 Mb (ftp)(http) BW
GSE157452_HKO_H3K4me1_ZT6_ChIP_merged.narrowPeak.gz 180.3 Kb (ftp)(http) NARROWPEAK
GSE157452_HWT_BMAL1_ZT6_ChIP_merged.bw 428.3 Mb (ftp)(http) BW
GSE157452_HWT_BMAL1_ZT6_ChIP_merged.narrowPeak.gz 171.9 Kb (ftp)(http) NARROWPEAK
GSE157452_HWT_H3K27ac_ZT6_ChIP_merged.bw 482.8 Mb (ftp)(http) BW
GSE157452_HWT_H3K27ac_ZT6_ChIP_merged.narrowPeak.gz 403.6 Kb (ftp)(http) NARROWPEAK
GSE157452_HWT_H3K4me1_ZT6_ChIP_merged.bw 287.1 Mb (ftp)(http) BW
GSE157452_HWT_H3K4me1_ZT6_ChIP_merged.narrowPeak.gz 806.8 Kb (ftp)(http) NARROWPEAK
GSE157452_Hep3B_BMAL1_merged.bw 471.0 Mb (ftp)(http) BW
GSE157452_Hep3B_HNF4A_merged.bw 328.0 Mb (ftp)(http) BW
GSE157452_HepG2_HNF4A_merged.bw 472.3 Mb (ftp)(http) BW
GSE157452_JL_HNF4A_ZT16_ChIP_merged.bw 583.9 Mb (ftp)(http) BW
GSE157452_JL_HNF4A_ZT16_ChIP_merged.narrowPeak.gz 50.5 Kb (ftp)(http) NARROWPEAK
GSE157452_JL_HNF4A_ZT4_ChIP_merged.bw 517.3 Mb (ftp)(http) BW
GSE157452_JL_HNF4A_ZT4_ChIP_merged.narrowPeak.gz 73.6 Kb (ftp)(http) NARROWPEAK
GSE157452_U2OS_GFP_BMAL1_merged.bed.gz 95.9 Kb (ftp)(http) BED
GSE157452_U2OS_GFP_BMAL1_merged.bw 486.6 Mb (ftp)(http) BW
GSE157452_U2OS_GFP_H3K27ac_merged.bed.gz 256.3 Kb (ftp)(http) BED
GSE157452_U2OS_GFP_H3K27ac_merged.bw 298.4 Mb (ftp)(http) BW
GSE157452_U2OS_GFP_H3K4me1_merged.bed.gz 395.2 Kb (ftp)(http) BED
GSE157452_U2OS_GFP_H3K4me1_merged.bw 291.6 Mb (ftp)(http) BW
GSE157452_U2OS_GFP_HNF4A8_control__BMAL1_merged.bed.gz 339.4 Kb (ftp)(http) BED
GSE157452_U2OS_GFP_HNF4A8_control__BMAL1_merged.bw 307.1 Mb (ftp)(http) BW
GSE157452_U2OS_HNF4A8_BMAL1_merged.bed.gz 267.9 Kb (ftp)(http) BED
GSE157452_U2OS_HNF4A8_BMAL1_merged.bw 188.5 Mb (ftp)(http) BW
GSE157452_U2OS_HNF4A_BMAL1_merged.bed.gz 75.5 Kb (ftp)(http) BED
GSE157452_U2OS_HNF4A_BMAL1_merged.bw 497.6 Mb (ftp)(http) BW
GSE157452_U2OS_HNF4A_H3K27ac_merged.bed.gz 215.1 Kb (ftp)(http) BED
GSE157452_U2OS_HNF4A_H3K27ac_merged.bw 286.1 Mb (ftp)(http) BW
GSE157452_U2OS_HNF4A_H3K4me1_merged.bed.gz 313.6 Kb (ftp)(http) BED
GSE157452_U2OS_HNF4A_H3K4me1_merged.bw 269.2 Mb (ftp)(http) BW
GSE157452_WT_ZT16_ATACseq_merged.broadPeak.gz 1.1 Mb (ftp)(http) BROADPEAK
GSE157452_WT_ZT16_ATACseq_merged.bw 431.8 Mb (ftp)(http) BW
GSE157452_WT_ZT6_ATACseq_merged.broadPeak.gz 801.4 Kb (ftp)(http) BROADPEAK
GSE157452_WT_ZT6_ATACseq_merged.bw 404.0 Mb (ftp)(http) BW
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