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Series GSE157507 Query DataSets for GSE157507
Status Public on Sep 05, 2020
Title Lymphatic endothelial cells contribute to blood vessel formation in tumours
Organisms Mus musculus; blank sample
Experiment type Expression profiling by high throughput sequencing
Summary Using multicolor lineage tracing, in vivo time-lapse imaging and single cell transcriptional profiling in a mouse glioma model, we identify tumour blood endothelial cells carrying a Csf1r lineage trace. These Csf1r lineage endothelial cells (CLECs) form up to 10% of the tumour vasculature and express endothelial cell markers as well as a unique set of genes that can also be found in single cell transcriptome data of tumour endothelium from various human tumours.
 
Overall design The transcriptomes of 768 single cells were sequenced (scRNAseq) after FACS sorting.
 
Contributor(s) Rambow F
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Submission date Sep 04, 2020
Last update date Jun 04, 2021
Contact name Florian Rambow
E-mail(s) Florian.Rambow@cme.vib-kuleuven.be
Organization name VIB
Street address Herestraat 49 box 912
City Leuven
ZIP/Postal code 3000
Country Belgium
 
Platforms (2)
GPL19057 Illumina NextSeq 500 (Mus musculus)
GPL29107 Illumina NextSeq 500 (blank sample)
Samples (768)
GSM4768116 KM1-A1_S1
GSM4768117 KM1-A2_S9
GSM4768118 KM1-A3_S17
Relations
BioProject PRJNA661541
SRA SRP280130

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE157507_2684.genes.reads.count.txt.gz 3.1 Mb (ftp)(http) TXT
GSE157507_2969.genes.reads.count.txt.gz 2.3 Mb (ftp)(http) TXT
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Raw data are available in SRA
Processed data are available on Series record

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