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Series GSE158788 Query DataSets for GSE158788
Status Public on Aug 08, 2021
Title Gene Expression Profile Analysis of Gallic Acid-induced Cell Death Process
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary Gallic acid is a natural phenolic compound that displays anti-cancer properties in clinically relevant cell culture and rodent models. To date, the molecular mechanism governing the gallic acid-induced cancer cell death process is largely unclear, thus hindering development of novel therapeutics. Therefore, we performed time-course long non-coding RNA sequencing (lncRNA-seq) to reveal the gene expression profiles at the early, middle, and late stages of the gallic acid-induced cell death process in human cervical cancer HeLa cells. This work provides a dataset with differentially expressed genes across different stages of cell death process during the gallic acid induction, which is important for further study on the control of this cell death mechanism.
Overall design There are 15 samples in total (5-time points x 3 replicates). Time points include: HeLa cells treated with gallic acid (50 µg/mL) for 0 hour (GA0hr), 2 hours (GA2hr), 4 hours (GA4hr), 6 hours (GA6hr), and 9 hours (GA9hr).
Contributor(s) Tang HM, Cheung CK
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Submission date Sep 30, 2020
Last update date Aug 08, 2021
Contact name Ho Man Holly Tang
Organization name The Chinese University of Hong Kong
Department School of Life Sciences
Lab Rm 381
Street address Science Centre South Block
City Shatin
ZIP/Postal code 00000
Country Hong Kong
Platforms (1)
GPL20301 Illumina HiSeq 4000 (Homo sapiens)
Samples (15)
GSM4810497 GA0hr_a
GSM4810498 GA0hr_b
GSM4810499 GA0hr_c
BioProject PRJNA666556
SRA SRP285879

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SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE158788_Annotated_lncRNA_FPKM.txt.gz 253.1 Kb (ftp)(http) TXT
GSE158788_Novel_lncRNA_FPKM.txt.gz 198.9 Kb (ftp)(http) TXT
GSE158788_TUCP_FPKM.txt.gz 210.2 Kb (ftp)(http) TXT
GSE158788_Transcript_FPKM.txt.gz 4.3 Mb (ftp)(http) TXT
GSE158788_mRNA_FPKM.txt.gz 4.1 Mb (ftp)(http) TXT
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Raw data are available in SRA
Processed data are available on Series record

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