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| Status |
Public on Oct 31, 2021 |
| Title |
Expression data from PBMCs infected with influenza A virus and treated with/without Itaconate |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
Analysis of gene expression in human PBMCs infected with influenza A virus or Mock and treated with Itaconic acid, Dimethyl itaconate or 4-Octyl itaconate to investigate the effects itaconate have on transcriptional response in human PBMCs.
We particularly looked at anti-inflammatory effects of itaconate in inflammation followed by Influenza A virus infection.
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| Overall design |
Human PBMCs were infected with influenza A viruses, or non-infected (Mock) for 12 hours. Infected PBMCs were treated to itaconic acid, dimethyl itaconate or 4-Octyl-itaconate. RNA was extracted, and subjected to transcriptome profiling array Clariom™ S Assay, human.
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| Contributor(s) |
Pessler F, Geffers R |
| Citation(s) |
35025971 |
| |
| Submission date |
Nov 26, 2020 |
| Last update date |
Jan 30, 2022 |
| Contact name |
Frank Pessler |
| E-mail(s) |
frank.pessler@twincore.de
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| Phone |
+49(511)220027167
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| Organization name |
Center for Experimental and Clinical Infection Research GmbH
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| Department |
Experimental Infection Research
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| Lab |
Research Group Biomarkers for Infectious Diseases
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| Street address |
Feodor-Lynen-Str. 7-9
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| City |
Hannover |
| ZIP/Postal code |
30625 |
| Country |
Germany |
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| Platforms (1) |
| GPL23159 |
[Clariom_S_Human] Affymetrix Clariom S Assay, Human (Includes Pico Assay) |
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| Samples (20)
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| Relations |
| BioProject |
PRJNA681009 |
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