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Series GSE163952 Query DataSets for GSE163952
Status Public on Jan 22, 2021
Title Neurodegeneration in herpes simplex virus 1 infected human brain organoids
Organisms Homo sapiens; Human alphaherpesvirus 1
Experiment type Expression profiling by high throughput sequencing
Summary We describe the cellular response to HSV-1 infection in human iPSC-derived brain organoids
 
Overall design Single-cell and bulk RNA-sequencing was performed from human brain organoids infected with HSV-1, at different time points post infection
 
Contributor(s) Rybak-Wolf A, Wyler E, Legnini I, Glažar P, Loewa A, Kim SJ, Pentimalli TM, Beyersdorf B, Oliveras Martinez A, Woehler A, Landthaler M, Rajewsky N
Citation(s) 37349587
Submission date Dec 28, 2020
Last update date Jan 30, 2024
Contact name Emanuel Wyler
E-mail(s) emanuel.wyler@mdc-berlin.de
Phone +49 30 9406 3009
Organization name Max Delbrück Center for Molecular Medicine
Department Berlin Institute for Medical Systems Biology
Lab RNA Biology and Posttranscriptional Regulation
Street address Robert Roessle Str 10
City Berlin
ZIP/Postal code 13125
Country Germany
 
Platforms (6)
GPL18573 Illumina NextSeq 500 (Homo sapiens)
GPL20301 Illumina HiSeq 4000 (Homo sapiens)
GPL26180 Sequel (Homo sapiens)
Samples (40)
GSM4991120 iPSC-2 line (Thermo Fisher A18945), 3dpi, replicate 1, for bulk RNA-seq
GSM4991121 iPSC-2 line (Thermo Fisher A18945), 3dpi, replicate 2, for bulk RNA-seq
GSM4991122 iPSC-2 line (Thermo Fisher A18945), 6dpi, replicate 1, for bulk RNA-seq
Relations
BioProject PRJNA688309
SRA SRP299538

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE163952_CTRL.rds.gz 938.2 Mb (ftp)(http) RDS
GSE163952_HSV1GFPtrunc_corr.fa.gz 42.3 Kb (ftp)(http) FA
GSE163952_HSV1GFPtrunc_corr.gtf.gz 2.2 Kb (ftp)(http) GTF
GSE163952_NR_AR_ORG_HSV1_1_gene_polyA_length.csv.gz 1.0 Mb (ftp)(http) CSV
GSE163952_NR_AR_ORG_HSV1_2_gene_polyA_length.csv.gz 373.6 Kb (ftp)(http) CSV
GSE163952_NR_AR_ORG_HSV1_3_gene_polyA_length.csv.gz 561.7 Kb (ftp)(http) CSV
GSE163952_NR_AR_ORG_HSV1_4_gene_polyA_length.csv.gz 815.0 Kb (ftp)(http) CSV
GSE163952_NR_AR_ORG_HSV1_5_gene_polyA_length.csv.gz 292.5 Kb (ftp)(http) CSV
GSE163952_NR_AR_ORG_HSV1_6_gene_polyA_length.csv.gz 304.6 Kb (ftp)(http) CSV
GSE163952_all_timepoints.rds.gz 7.1 Gb (ftp)(http) RDS
GSE163952_hg38HSV1GFPtc.Seurat.500.RDS.gz 2.1 Gb (ftp)(http) RDS
GSE163952_merged_raw_read_counts.txt.gz 574.3 Kb (ftp)(http) TXT
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Raw data are available in SRA
Processed data are available on Series record

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