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| Status |
Public on Mar 27, 2023 |
| Title |
CUT&RUN analysis of murine wt NPCs grown in alone and in co-culture with primary brain microvascular endothelial cells |
| Organism |
Mus musculus |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
We previously established co-culture assay in which NPCs acquire phenotypic hallmarks of quiescence upon direct cell-cell contact with primary brain microvascular endothelial cells (bmvEC). Here, we used this in vitro assay to identify the mechanisms by which p53 enforces quiescence
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| Overall design |
The experiment was conducted to identify the direct binding sites of p53 at response elements upon co-culture-induced quiescence in mouse NPCs
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| Contributor(s) |
Parrinello S, Marguerat S |
| Citation(s) |
37084728 |
| Submission date |
Jan 29, 2021 |
| Last update date |
Nov 16, 2023 |
| Contact name |
LMS Bioinformatics Core |
| E-mail(s) |
bioinformatics@lms.mrc.ac.uk
|
| Organization name |
MRC London Institute of Medical Sciences
|
| Department |
Bioinformatics Core
|
| Street address |
Hammersmith Hospital Campus, Du Cane Road
|
| City |
London |
| ZIP/Postal code |
W12 0NN |
| Country |
United Kingdom |
| |
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| Platforms (1) |
| GPL19057 |
Illumina NextSeq 500 (Mus musculus) |
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| Samples (4)
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| Relations |
| BioProject |
PRJNA697942 |
| SRA |
SRP303851 |
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