To investigate the role of miRNAs in the etiology of idiopathic PD, we conducted global miRNA expression profiling in peripheral blood mononuclear cells (PBMCs) of PD patients and controls.
Overall design
Total RNA was extracted from the PBMCs of 19 PD patients and 13 controls, labeled and hybridized to Exiqon microarrays spotted with probes for 733 human miRNAs.