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Series GSE168368 Query DataSets for GSE168368
Status Public on Apr 12, 2023
Title Myeloproliferative neoplasms show different signature in megakaryocyte-erythroid progenitors among different subtypes
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary In this study, we explored the transcriptome of megakaryocyte-erythroid progenitors (MEPs) in JAK2 V617F+ PV and ET and found distinctive gene expression patterns within MPN subtypes. The differentially expressed genes (DEGs) indicated that cellular processes and signaling pathways in MEPs from healthy donors (HDs, or NCs) are differentially modulated in PV and ET patients.
Overall design Examination of gene expression in 2 different MPN subtypes as well as HDs (NCs) at MEP stage.
Contributor(s) Tong J, Ju M, Zhang L, Shi L
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Submission date Mar 05, 2021
Last update date Apr 13, 2023
Contact name Coral Tong
Organization name Institute of Hematology & Blood Disease Hospital
Street address 288 Nanjing Rd, Heping
City Tianjin
ZIP/Postal code 300020
Country China
Platforms (1)
GPL11154 Illumina HiSeq 2000 (Homo sapiens)
Samples (29)
GSM3030306 PV1MEP
GSM3030307 PV2MEP
GSM3030308 PV3MEP
BioProject PRJNA707039
SRA SRP310755

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE168368_gene_count_matrix.csv.gz 1.3 Mb (ftp)(http) CSV
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Raw data are available in SRA
Processed data are available on Series record

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