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Series GSE16853 Query DataSets for GSE16853
Status Public on Jan 01, 2010
Title Expression data from Foxl2 wild-type and mutant ovaries and testes
Organism Mus musculus
Experiment type Expression profiling by array
Summary Foxl2 is a forkhead transcription factor expressed only in the female, but not in the male gonad. We have created mice homozygous mutant for the Foxl2 gene (KO) as well as mice carrying a conditional mutant Foxl2 allele (floxed).
The expression profiles of conventional Foxl2 knockout and wildtype ovaries were compared at P3, using the Affy Mouse Genome 430 2.0 Array. Adult wildtype and conditional mutant (Foxl2 floxed x RosaCre-EBD treated with tamoxifen) ovaries were compared to adult wildtype testes using the Affymetrix Mouse Gene 1.0 ST Array. Both experiments (KO/WT P3 and Mutant/WT/Testis Adult were also compared to each other.)
Overall design Ovaries from newborn (postnatal day 3) and adult (8 week old) mice were excised from the animal and RNA was prepared from whole ovaries (Adult testes were excised and RNA was isolated from 1/4 testis).
Contributor(s) Uhlenhaut H
Citation(s) 20005806
Submission date Jun 26, 2009
Last update date Mar 04, 2019
Contact name Henriette Uhlenhaut
Phone +496221387432
Organization name EMBL
Department Developmental Biology Unit
Lab Treier
Street address Meyerhofstrasse 1
City Heidelberg
ZIP/Postal code 69117
Country Germany
Platforms (2)
GPL1261 [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array
GPL6246 [MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [transcript (gene) version]
Samples (12)
GSM422391 Adult testis, wild-type, replicate 1
GSM422392 Adult testis, wild-type, replicate 2
GSM422393 Adult testis, wild-type, replicate 3
BioProject PRJNA117553

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Supplementary file Size Download File type/resource
GSE16853_RAW.tar 65.7 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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