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Series GSE17288 Query DataSets for GSE17288
Status Public on Jul 29, 2009
Title CGH Salivary Gland - Y cn bw sp
Project modENCODE
Organism Drosophila melanogaster
Experiment type Genome variation profiling by genome tiling array
Summary modENCODE_submission_720
This submission comes from a modENCODE project of David MacAlpine. For full list of modENCODE projects, see
Project Goal: Most terminally differentiated Drosophila tissues are either polyploid or polytene. Unlike normal chromosomes, where the entire chromosome must be replicated exactly once, polytene chromosomes are often differentially replicated with many regions underreplicated and some overreplicated. We will characterize five different polytene tissues using comparative genomic hybridization (CGH) to identify differentially replicated regions of each chromosome. These studies will also identify tissue specific amplicons, where the replication mediated amplification of specific loci is essential for up-regulation of mRNA levels encoding proteins critical for development. The differential replication of polytene chromosomes in Drosophila will provide a unique opportunity to understand how developmental cues and chromosomal domains influence replication initiation.

Keywords: CGH

For data usage terms and conditions, please refer to and
Overall design EXPERIMENT TYPE: CGH. BIOLOGICAL SOURCE 1: Strain: Y cn bw sp; Tissue: larval salivary gland; Genotype: y[1] oc[R3.2]; Gr22b[1] Gr22d[1] cn[1] CG33964[R4.2] bw[1] sp[1]; LysC[1] lab[R4.2] MstProx[1] GstD5[1] Rh6[1]; Sex: Unknown; BIOLOGICAL SOURCE 2: Strain: Y cn bw sp; Developmental Stage: Embryo 0-4h; Sex: Unknown; NUMBER OF REPLICATES: 1; EXPERIMENTAL FACTORS: Tissue larval salivary gland
Web link
Contributor(s) MacAlpine D, Orr-Weaver T, Eng T
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BioProject PRJNA63463
Submission date Jul 23, 2009
Last update date Jun 28, 2012
Contact name DCC modENCODE
Phone 416-673-8579
Organization name Ontario Institute for Cancer Research
Street address MaRS Centre, South Tower, 101 College Street, Suite 800
City Toronto
State/province Ontario
ZIP/Postal code M5G 0A3
Country Canada
Platforms (1)
GPL7787 Agilent_Dm_5.1_470_tiling
Samples (1)
GSM432735 orr_weaver_salivary_1 extraction1_array1

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE17288_MA2C_Orr-Weaver_251663510028_normalized.txt.gz 1.8 Mb (ftp)(http) TXT
GSE17288_RAW.tar 82.6 Mb (http)(custom) TAR (of TXT)
GSE17288_salivary_244_MA2Cscore.wig.gz 1.2 Mb (ftp)(http) WIG
GSE17288_salivary_244_trough_peaks.gff.gz 1.3 Kb (ftp)(http) GFF
Processed data are available on Series record

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