NCBI Logo
GEO Logo
   NCBI > GEO > Accession DisplayHelp Not logged in | LoginHelp
GEO help: Mouse over screen elements for information.
          Go
Series GSE17291 Query DataSets for GSE17291
Status Public on Jul 29, 2009
Title CGH Follicle OregonR-Orr-Weaver
Project modENCODE
Organism Drosophila melanogaster
Experiment type Genome variation profiling by genome tiling array
Summary modENCODE_submission_724
This submission comes from a modENCODE project of David MacAlpine. For full list of modENCODE projects, see http://www.genome.gov/26524648
Project Goal: Most terminally differentiated Drosophila tissues are either polyploid or polytene. Unlike normal chromosomes, where the entire chromosome must be replicated exactly once, polytene chromosomes are often differentially replicated with many regions underreplicated and some overreplicated. We will characterize five different polytene tissues using comparative genomic hybridization (CGH) to identify differentially replicated regions of each chromosome. These studies will also identify tissue specific amplicons, where the replication mediated amplification of specific loci is essential for up-regulation of mRNA levels encoding proteins critical for development. The differential replication of polytene chromosomes in Drosophila will provide a unique opportunity to understand how developmental cues and chromosomal domains influence replication initiation.

Keywords: CGH

For data usage terms and conditions, please refer to http://www.genome.gov/27528022 and http://www.genome.gov/Pages/Research/ENCODE/ENCODEDataReleasePolicyFinal2008.pdf
 
Overall design EXPERIMENT TYPE: CGH. BIOLOGICAL SOURCE 1: Strain: Oregon-R Orr-Weaver; Tissue: oocyte associated follicle cell; Genotype: TBA; Sex: Female; BIOLOGICAL SOURCE 2: Strain: Oregon-R Orr-Weaver; Developmental Stage: Embryo 0-4h; Genotype: TBA; Sex: Unknown; NUMBER OF REPLICATES: 1; EXPERIMENTAL FACTORS: Tissue oocyte associated follicle cell
Web link http://www.ncbi.nlm.nih.gov/projects/geo/info/ENCODE.html
 
Contributor(s) MacAlpine D, Orr-Weaver T, Eng T
Citation missing Has this study been published? Please login to update or notify GEO.
BioProject PRJNA63463
Submission date Jul 23, 2009
Last update date Jun 28, 2012
Contact name DCC modENCODE
E-mail(s) help@modencode.org
Phone 416-673-8579
Organization name Ontario Institute for Cancer Research
Lab modENCODE DCC
Street address MaRS Centre, South Tower, 101 College Street, Suite 800
City Toronto
State/province Ontario
ZIP/Postal code M5G 0A3
Country Canada
 
Platforms (1)
GPL7788 Agilent_Dm_4.3_612_tiling
Samples (1)
GSM432742 orr_weaver_follicle_1 extraction1_array1

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE17291_MA2C_Orr-Weaver_251476110027_normalized.txt.gz 1.3 Mb (ftp)(http) TXT
GSE17291_RAW.tar 61.8 Mb (http)(custom) TAR (of TXT)
GSE17291_follicle_188_MA2Cscore.wig.gz 899.5 Kb (ftp)(http) WIG
GSE17291_follicle_188_peaks.gff.gz 259 b (ftp)(http) GFF
Processed data are available on Series record

| NLM | NIH | GEO Help | Disclaimer | Accessibility |
NCBI Home NCBI Search NCBI SiteMap