GEO Logo
   NCBI > GEO > Accession DisplayHelp Not logged in | LoginHelp
GEO help: Mouse over screen elements for information.
Series GSE17387 Query DataSets for GSE17387
Status Public on Feb 10, 2010
Title Genome-wide Promoter Mapping of Histone H3 Lysine 4 and Lysine 27 Methylation in Preimplantation Embryos
Organism Mus musculus
Experiment type Methylation profiling by genome tiling array
Summary First lineage specification in the mammalian blastocyst embryo leads to formation of the inner cell mass (ICM) and trophectoderm (TE), which respectively give rise to the embryo proper and extraembryonic tissues. We show histone methylation asymmetry on promoters in the first two developmental lineages, and highlight epigenetic skewing associated with derivation of embryonic stem (ES) cells.
Overall design Comparison of histone methylation patterns on promoters in the ICM, TE and in ES cells derived from ICM. ChIP-chip experiments using anti-H3K4me3 or anti-H3K27me3 antibodies. Two or three replicates per sample.
Contributor(s) Dahl J, Reiner A, Collas P
Citation(s) 20161773
Submission date Jul 28, 2009
Last update date Mar 21, 2012
Contact name Philippe Collas
Organization name University of Oslo
Department Institute of Basic Medical Sciences
Street address PO Box 1112 Blindern
City Oslo
ZIP/Postal code 0317
Country Norway
Platforms (1)
GPL8943 2006-07-18_MM8_RefSeq_promoter
Samples (16)
GSM434416 ICM_k4m3_rep1
GSM434417 ICM_k4m3_rep2
GSM434418 ICM_k4m3_rep3
BioProject PRJNA118821

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE17387_RAW.tar 250.5 Mb (http)(custom) TAR (of PAIR)
Processed data included within Sample table

| NLM | NIH | GEO Help | Disclaimer | Accessibility |
NCBI Home NCBI Search NCBI SiteMap