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Series GSE17684 Query DataSets for GSE17684
Status Public on Oct 05, 2010
Title Widespread over-expression of the X chromosome in sterile F1 hybrid mice
Platform organism Mus musculus
Sample organisms Mus musculus; Mus musculus domesticus; Mus musculus musculus x M. m. domesticus
Experiment type Expression profiling by array
Summary We used a reciprocal cross of Mus musculus and M. domesticus in which F1 males are sterile in one direction and fertile in the other direction, in order to associate expression differences with sterility.
Overall design Four different crosses were performed. A cross between two strains within each mouse species (M. musculus, PWK/PhJ and CZECHII/EiJ; M. domesticus, LEWES/EiJ and WSB/EiJ). And two reciprocal crosses between a domesticus (LEWES/EiJ) and a musculus (PWK/PhJ) strain. The cross between a musculus female and a domesticus male produces sterile male offspring - whereas all other crosses produced fertile male offspring. Testis tissue from three male mice (60 days old) from all four crosses were analysed on the Affymetrix MG 430.2. Array.
Contributor(s) Good JM, Giger T, Dean MD, Nachman MW
Citation(s) 20941395
Submission date Aug 17, 2009
Last update date Mar 21, 2012
Contact name Thomas Giger
Organization name Max-Planck-Institute of Evolutionary Anthropology
Department Evolutionary Genetics
Street address Deutscher Platz 6
City Leipzig
ZIP/Postal code 04106
Country Germany
Platforms (1)
GPL6886 Mouse Genome 430 2.0 Array [Mouse4302_Mm_ENSG (v11.0.1) CDF]
Samples (12)
GSM441173 testis fertile M. domesticus rep1
GSM441174 testis fertile M. domesticus rep2
GSM441175 testis fertile M. domesticus rep3
BioProject PRJNA118417

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Supplementary file Size Download File type/resource
GSE17684_RAW.tar 53.6 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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