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| Status |
Public on Jun 16, 2021 |
| Title |
Transcriptomic, proteomic and phosphoproteomic underpinnings of daily exercise performance and Zeitgeber activity of endurance training in mouse skeletal muscle |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
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| Summary |
Running at different times of the day resulted in a vastly different activation of signaling pathways, e.g., related to stress response, vesicular trafficking, repair, and regeneration.
Second, voluntary wheel running at the opposite phase of the dark, feeding period surprisingly revealed minimal Zeitgeber (i.e., synchronizing) activity of training.
This integrated study provides important insights into the circadian regulation of endurance performance and the control of the circadian clock by exercise.
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| Overall design |
Investigating the effect of acute treadmill exercise and voluntary chronic wheel running exercise on the transcriptomic, proteomic and phosphoproteomic level at different times of the day in mouse skeletal muscle
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| Contributor(s) |
Maier G, Delezie J, Westermark PO, Santos G, Ritz D, Handschin C |
| Citation(s) |
34142717 |
| |
| Submission date |
Jun 15, 2021 |
| Last update date |
Sep 15, 2021 |
| Contact name |
Christoph Handschin |
| Organization name |
Biozentrum, University of Basel
|
| Street address |
Spitalstrasse 41
|
| City |
Basel |
| ZIP/Postal code |
4056 |
| Country |
Switzerland |
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| Platforms (1) |
| GPL19057 |
Illumina NextSeq 500 (Mus musculus) |
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| Samples (40)
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| Relations |
| BioProject |
PRJNA738158 |
| SRA |
SRP324159 |
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