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Series GSE179031 Query DataSets for GSE179031
Status Public on May 05, 2023
Title The transcription factor Foxp1 regulates aerobic glycolysis in adipocytes and myocytes
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary The goal of this study was to apply Next Generation Sequencing analyses to identify genes and pathways regulated by the Foxp1 transcription factor in 3T3-L1 adipocytes. We found, that series of genes involved in metabolism, glycolysis, signal transduction, as well as nervous system development are regulated in response to overexpression and knock down of this transcription factor, thereby providing important insight into biological role of Foxp1 for cells survival and metabolism.
 
Overall design Next Generation Sequencing analyses of 3T3-L1 adipocytes with overexpression and downregulation of Foxp1
Web link https://doi.org/10.1016/j.jbc.2023.104795
 
Contributor(s) Enerback S, Ma H, Sukonina V, Zhang W, Kanduri C, Subhash S
Citation(s) 37150320
Submission date Jun 28, 2021
Last update date May 08, 2023
Contact name Santhilal Subhash
Organization name Cold Spring Harbor Laboratory
Department Cancer center
Street address 1 bungtown road
City Cold Spring Harbor
State/province New York
ZIP/Postal code 11724
Country USA
 
Platforms (1)
GPL13112 Illumina HiSeq 2000 (Mus musculus)
Samples (12)
GSM5404011 Foxp1_Control_replicate1_overexpression_RNA-seq
GSM5404012 Foxp1_Control_replicate2_overexpression_RNA-seq
GSM5404013 Foxp1_Control_replicate3_overexpression_RNA-seq
Relations
BioProject PRJNA741986
SRA SRP325847

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE179031_Mus_musculus.GRCm38.98_expression_profile_RPKM_matrix.txt.gz 1.0 Mb (ftp)(http) TXT
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Raw data are available in SRA
Processed data are available on Series record

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