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Series GSE179265 Query DataSets for GSE179265
Status Public on Dec 15, 2021
Title Inflammatory molecular endotypes of nasal polyps derived from Caucasian and Japanese populations
Organism Homo sapiens
Experiment type Expression profiling by high throughput sequencing
Summary Chronic rhinosinusitis with nasal polyps is a hallmaerk disease in the field of upper airway immunity and chronic inflammation. Diverse inflammatory patterns between nasal polyps have been described in patients that hail from disparate racial and geographic backgrounds. However, it remains unclear whether these immunologic differences in nasal polyps between racial groups are driven by unique molecular mechanisms. We interrogated the gene expression profiles of nasal polyp tissues from Western (United States) and East Asian (Japan) descent, compared to ethmoid sinus tissue controls.
Overall design Examination of the molecular differences between Caucasian (n=8), Asian CRSwNP (n=9), and contol (n=7) using whole-transcriptome RNA sequencing.
Contributor(s) Nakayama T, Lee I, Ziang S, Nayak JV
Citation(s) 34863854
Submission date Jul 01, 2021
Last update date Dec 15, 2021
Contact name Tsuguhisa Nakayama
Organization name Stanford University
Department Department of Otolaryngology-Head and Neck Surgery
Street address 801 Welch Road
City Stanford
State/province CA
ZIP/Postal code 94305
Country USA
Platforms (1)
GPL24676 Illumina NovaSeq 6000 (Homo sapiens)
Samples (24)
GSM5412745 Control uncinate process 1
GSM5412746 Control uncinate process 2
GSM5412747 Control uncinate process 3
This SubSeries is part of SuperSeries:
GSE179269 Inflammatory molecular endotypes of nasal polyps derived from Caucasian and Japanese populations
BioProject PRJNA743028
SRA SRP326492

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SOFT formatted family file(s) SOFTHelp
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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE179265_readcount_genename.txt.gz 2.7 Mb (ftp)(http) TXT
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Raw data are available in SRA
Processed data are available on Series record

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